The supply chain is the beating heart of the industrial sector. Properly managed incoming and outgoing flows have become a competitive advantage that companies have not to underestimate. The fourth industrial revolution is underway in all sectors that need digitisation, networking, cloud computing and data security. In recent years, companies have made huge strides in optimizing supply chains and logistics, significantly reducing costs and increasing efficiency. For operators in the logistics sector, this translates into the goal of minimizing the daily fixed costs of activities, fuel consumption, maintenance and hourly cost of resources. In particular, the rules that define the processes for shipping, truck loading, deliveries, etc. must be optimized. The first step is to collect data and information for processing and seek the best solutions to ensure effective operation. Clearly, logistics optimization models will be successful if employees follow the optimized plan. Effective solutions in a reasonable time. All this technology, however, requires people to have the necessary skills to manage and use data, models and software. Automation solutions can’t simply provide information to a single warehouse, but must bring benefits to the entire supply chain. Improved efficiency and new business models offer new opportunities to create value. Digitisation gives logistics the opportunity to offer new services and create new business models.